Professor, Institute of Environment, Health and Societies, Brunel University London
Andreas Kortenkamp is professor for human toxicology at the Institute of Environment, Health and Societies, Brunel University London. His research interests are in exploring environmental pollutants and their combined effects on endocrine diseases and other adverse health outcomes.
He has published numerous papers on the prediction and experimental evaluation of combination effects of estrogenic, anti-androgenic and genotoxic chemicals. Professor Kortenkamp has served on the US National Academy of Sciences Panel on mixture risk assessment for phthalates, and on the National Academy of Sciences Panel investigating non-monotonic dose-response relationships. On the recommendation of the president of the US National Academy of Sciences, he became a member of the US Consumer Health Advisory Panel on the assessment of phthalates. He has produced the State of the Art Report on Mixture Toxicology for the European Commission, DG Environment. In 2012 he completed the State of the Art Assessment of Endocrine Disrupters for the European Commission. He was a member of the World Health Organisation / United Nation Environmental Programme panel for evaluating the state of the science of endocrine disruption 2012.
He was involved with several working groups of the European Food Safety Authority on developing grouping criteria for mixture risk assessment for pesticides. Andreas is the coordinator of the EU-funded ATHENA project which aims to develop test methods for thyroid hormone disrupting chemicals. He participates in the Human Biomonitoring for EU project with work on combined exposures, and is a partner in the ATHLETE project, a new EU-funded consortium on the human exposome. He earned his Ph.D. from Bremen University, Germany, and in 2001 started his academic career at the School of Pharmacy, University of London. In July 2011 he joined Brunel University, West London.
Associate Professor, McGill University
Canada Research Chair, Tier II, Epigenetics, Reproduction and Development
Department of Animal Science, Faculty of Agricultural and Environmental Sciences
Appointment and Education
Dr. Sarah Kimmins received her Ph.D. from Dalhousie University in 2003 and completed her post-doctoral training at the Institut de Génétique et de Biologie Moleculaire et Cellulaire in Strasbourg, France. She was appointed to the Department of Animal Science in the Faculty of Agricultural and Environmental Sciences in September of 2005 and is a tenured Associate Professor.
Leadership and Service
Her independent and collaborative research programs have received peer reviewed funding from the Canadian Institutes of Health Research (CIHR), Genome Quebec, the National Institutes for Health, Fonds québéc de la recherché sur la nature et les technologies (FQRNT) and the National Sciences and Engineering Research Council (NSERC). In 2014 she received the Young Andrologist Award from the American Society of Andrology, and in 2016 the Society for the Study of Reproduction Young Investigator award.
Globally the prevalence of infertility, diabetes, obesity, and diseases such as cancer and cardiovascular disease are on the rise. These increases have occurred at rates that cannot be due to changes in the genetic structure of the population, and are likely caused by environmental factors that modify gene function via epigenetics. Kimmins leads a research program focussed on determining how the environment (BMI, nutrients and toxicants) impacts the fertility of parents and development and health of offspring. Her research involves fundamental multi-generational studies in mouse models to identify the mechanisms implicated in epigenetic inheritance. Key discoveries include linking paternal diets to an altered sperm epigenome and birth defects in offspring (Lambrot et al., 2013; Nature Communications).
Associate Professor, North-West University
Rialet is an associate professor at the North-West University's research unit for Environmental Sciences and Management. She holds a PhD in Zoology, but the focus of the research was persistent organic pollutants in the aquatic systems of South Africa. Since the completion of her PhD, she has expanded her interest into quantifying endocrine disrupting effects using reporter gene cell lines. This has led to sampling abiotic matrices all over the country, and testing its extracts for endocrine disruption.
She has been the supervisor/co-supervisor of 11 MSc and 4 PhD students in the field of ecotoxicology. She lectures zoology to second year students and has been doing this since 1997.
Professor, Institute for Risk Assessment Sciences (IRAS), Utrecht University
Juliette Legler is Professor of Toxicology and Head of the Division of Toxicology at the Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University. She is also affiliated with the Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University.
Prior to joining IRAS in January 2018, she was employed at Brunel University London, where she was leader of the Environment and Health Theme within Brunel’s Institute for Environment, Health and Societies. She remains affiliated with Brunel as Honorary Professor of Toxicology and Environmental Health. From 2001 to 2015, she worked at the Institute for Environmental Studies, Vrije Universiteit Amsterdam (VU), where she was appointed Professor of Toxicology and Environmental Health in 2013. Prof. Legler is a European Registered Toxicologist and President of the Netherlands Society of Toxicology. Her research focusses on the molecular mechanisms of toxicity of chemicals and the effects of chemical exposure on humans, animals and the environment (One Health).
Since January 1, 2019, she has coordinated the 5 year EU H2020 project GOLIATH (Generation of Novel, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds (MDCs)), a consortium comprised of world-leading experts in endocrinology, molecular biology, toxicology, epidemiology, test method development, validation and chemical regulation. GOLIATH addresses the worldwide rise in metabolic disorders such as obesity, diabetes and fatty liver by developing much needed in vitro and alternative methods to identify metabolism disrupting chemicals. Prof. Legler is also coordinator of the ‘European Cluster to Improve Identification of Endocrine Disruptors’ (EURION), a cluster of eight new research projects on testing strategies for EDCs in Europe.
VANESSA M. HAYES
Petre Chair of Prostate Cancer Research, University of Sydney
Professor, Garvan Institute of Medical Research, Sydney
Extraordinary Professor of Public Health, University of Pretoria
Honorary Professor of Health Sciences, University of Limpopo
Vanessa is the Petre Chair of Prostate Cancer Research at the University of Sydney, Head and Professor of the Laboratory for Human Comparative and Prostate Cancer Genomics at the Garvan Institute of Medical Research in Sydney, Australia, Extraordinary Professor of Public Health at the University of Pretoria and Honorary Professor of Health Sciences at the University of Limpopo. Her research interest is in using the variation in the human genome to define human origins and evolution, and how genome variation triggers, drives and ultimately defines treatment for prostate cancer.
South African born and a graduate of Stellenbosch University, Vanessa completed her PhD in Cancer Genetics in 1999 at the University of Groningen in the Netherlands, applying novel genetic tools to clinical questions in carcinogenesis. After briefly leading a Genetics Laboratory within the Urology Department at Tygerberg Hospital, although focusing on genetic risk factors associated with HIV/AIDS, she became interested in the notable disparity in prostate cancer risk in outcomes in men of African versus European ancestries.
Her prostate cancer research took off in 2003, when Vanessa joined the Garvan Institute for Medical Research in Sydney, as head of the Cancer Genetics Laboratory. This work awarded her the Cancer Institute of New South Wales Premier’s Award for Cancer Research Fellow, an Australian Young Tall Poppy Award for Science and the Australian Academy of Science Inaugural Ruth Stephens Gani Medal for Human Genetics. She also represented Australia as a Fulbright Professional Scholar to the United States in 2009.
Vanessa has never forgotten her roots. In 2010 she led a large research effort to generate the first African and first KhoiSan complete human genomes, including that of Archbishop Desmond Tutu. As Scientific Director for the Southern African Prostate Cancer Study (SAPCS), Vanessa has been using genomics to understand the significant ethnic-based disparity in prostate cancer. Most recently the SAPCS team led the first African-based prostate cancer genome project.
Professor, Universitas Miguel Hernandez
Chair of the EDC's Advisory Group of the Endocrine Society
Angel Nadal studied chemistry (1984-1987) at the University of Alicante, and Biochemistry and Molecular Biology (1987-1989) at The Autonomous University of Madrid. He obtained his PhD at the Institute of Neuroscience, University of Alicante (1992), and trained as a postdoctoral fellow at The Physiology Group, Biomedical Science Division, King’s College London, UK (1993-1996).
Since 1997 he has been a member of the department of Physiology at Universitas Miguel Hernandez, where he became Professor of Physiology in 2009. In 1998 he started a research line to better understand the role that extranuclear actions of estrogen receptors have in the endocrine pancreas. The findings of this research line have been important to molecularly understand low dose effects triggered by Endocrine Disrupting Chemicals (EDCs) with estrogenic activities, mainly bisphenol-A. In 2006, his research group demonstrated that bisphenol-A exposure induced hyperinsulinemia and insulin resistance in adult male mice. During the last decade, they probed that bisphenol-A exposure during pregnancy predisposed male offspring as well as treated dames to type 2 diabetes mellitus. These findings have been seminal to establish the link between EDC exposure and diabetes mellitus. His interest continues in studying how the environment affects β-cell division, death and function and its implication in diabetes development. He has been recognized by the Spanish Society of Diabetes award to the best young investigator (2004) and The Alberto Sols award to basic diabetes research (2017).
During the last decade, he has been an invited speaker at more than 50 scientific meetings and seminars in America, Asia, Africa, and Europe. He is regularly involved in improving translation of EDC science into regulation. Since 2017 he has been the Chair of the EDCs Advisory Group of the Endocrine Society. To date, he has authored over 125 articles in journals with impact factor.
Sally Perreault Darney
Ph.D, Editor-in-Chief of Environmental Health Perspectives
National Institutes of Environmental Health Sciences, NIH
Sally Perreault Darney, PhD, is an internationally recognized researcher and editor in the fields of reproductive biology and environmental health. She currently serves as the Editor-in-Chief of Environmental Health Perspectives (EHP), a high impact journal of peer-reviewed research and news published by the National Institute for Environmental Health Sciences (NIEHS) of the U.S. National Institutes of Health.
After earning her PhD from the University of Hawaii and completing a postdoctoral fellowship at The Johns Hopkins University, she spent most of her career in the Office of Research and Development of the U.S. Environmental Protection Agency (EPA). There she conducted and directed “mission oriented” research designed to measure and evaluate the effects of environmental exposures on reproductive function and health. In this capacity she interfaced with Federal, State, and local risk assessors and contributed to reproductive and development test and risk assessment guidelines that have been adopted in the US and globally. She also served in research planning and advisory capacities for the EPA-NIEHS Children’s Centers Research Program, the U.S. National Children’s Study, and ORD’s National Research Programs in Human Health and in Chemical Safety.
She has published over 150 original research articles and reviews and served as an Associate Editor for Biology of Reproduction and Editor-in-Chief of the Journal of Andrology. Her life’s work is helping to ensure that important biomedical and environmental health decisions and policies are based on reliable scientific evidence.
Ph.D, Department of Microbiology, Stellenbosch University
Dr. Edward Archer is an Environmental Research Scientist at the Department of Microbiology, Stellenbosch University. He received his undergraduate degree in Biodiversity and Ecology at Stellenbosch University, from which he continued with Hons. and MSc. degrees in Zoology and a PhD in Microbiology at the same institution.
His research interest includes monitoring approaches to investigate the fate and subsequent environmental- and public health risk assessment of regularly-used pharmaceutical and personal care products (PPCPs) and endocrine-disrupting contaminants (EDCs) in freshwater ecosystems and wastewater treatment processes. His research contributes to various multi-stakeholder engagements with both local- and international industry and academia.
He is currently involved in various multi-disciplinary research projects with collaborators from the University of Bath (United Kingdom), the Water Research Commission and local wastewater treatment service providers to address global health challenges such as environmental pollution from urban dwellings, antimicrobial resistance development and risk characterisation of non-communicable disease using urban water profiling and wastewater-based epidemiology.
Ph.D, U.S. National Institute of Environmental Health Sciences
Thaddeus (Thad) Schug, Ph.D., is a Scientific Program Administrator at the U.S. National Institute of Environmental Health Sciences (NIH/NIEHS). He directs research programs in areas of male and female reproduction, metabolism, the development and disruption of the endocrine systems, developmental origins of health and disease (DOHaD), and cardiovascular health.
Thad received his Doctorate in Nutrition and Biomedical Sciences and a Master’s in Physics from Cornell University. His graduate work focused on the relationships between nuclear hormone receptor activation and various forms of cancer. Thad conducted his postdoctoral studies at the National Institutes of Health, where he investigated gene regulations involved in the aging process, homeostasis, metabolism, and inflammation.
Heather B. Patisaul
Ph.D, Associate Dean for Research, College of Sciences
Professor of Biological Sciences in the Center for Human Health and the Environment
North Carolina State University
Heather Patisaul received her B.S. in Zoology from the University of Florida and her Ph.D. from Emory University in Population Biology, Ecology and Evolution with an emphasis on brain/environment interactions. She completed postdoctoral training at the Yerkes National Primate Center and then CIIT in Research Triangle Park, North Carolina. At NCSU since 2006, her research explores the mechanisms by which exposure to endocrine disruptors, particularly during perinatal development, impacts sex-specific neuroendocrine physiology and behavior. Compounds of interest include Bisphenol A (BPA), phytoestrogens, and fire retardants.
Dr. Patisaul was named a NIEHS ONES Award recipient in 2007, and is currently a member of the NIEHS TARGET II consortium and the NIEHS CLARITY-BPA consortium, which also includes scientists at the National Toxicology Program and the National Center of Toxicological Research, to evaluate the endocrine disrupting properties of BPA. Dr. Patisaul has participated in over 20 national and international expert panels and workshops on health effects associated with neurotoxicants and endocrine disruptors, including the 2012 Workshop on Low Dose Effects of Endocrine Active Chemicals co-organized by the US National Institute for Environmental Health Sciences (NIEHS) and the Joint Research Centre's Institute for Health and Consumer Protection, and two National Academy of Sciences panels. She chaired the 2016 Gordon Research Conference on Environmental Endocrine Disruptors and is an active member of the Society for Neuroscience, the Society for Behavioral Neuroscience, the Society of Toxicology and the Endocrine Society where she participates in working groups on endocrine disruptors and adverse outcome pathway (AOP) development. She is also a member of the Endocrine Society’s Advocacy and Public Outreach Core Committee. Dr. Patisaul has published over 70 papers and co-authored the 2017 book Endocrine Disruptors, Brain and Behavior.
Part-time Professor, Department of Human Nutrition, University of Pretoria
Una MacIntyre is a part-time professor in the Department of Human Nutrition in the Faculty of Health Sciences, University of Pretoria, where her primary responsibilities are postgraduate research training and supervision. She holds a PhD in nutrition.
Her research focus is dietary intake assessment and the development of age and culture appropriate dietary assessment instruments. She is a National Research Foundation C-rated scientist and an associate editor for Public Health Nutrition.
Vice-Dean: Teaching and Learning, Faculty of Science, University of Johannesburg
Ina Wagenaar is currently Vice-Dean: Teaching and Learning in the Faculty of Science at the University of Johannesburg. She keeps a balance between managing the Teaching and Learning Plan in the Faculty of Science and her own teaching, research, and participation in community engagement. Since 2004, after completing her PhD in Aquatic Health, she has received her own research funding from the National Research Foundation which enabled her to manage her own research projects. More than 30 MSc and PhD students graduated under her supervision, which resulted in several publications in international peer reviewed journals and being rated (C2) as a researcher by the NRF since 2013.
The focus of her research is on fish health and reproduction. The Aquatic Health Research Group strives to do high quality research on the cause-and-effect relationship between toxicant exposure and the associated histopathological and reproductive effects in fish. The research approach includes both field surveys of wild fish inhabiting rivers and dams, as well as controlled laboratory exposure studies. The applied methodology involves a histology-based fish health assessment protocol that allows the identification of abnormalities on cellular level.
Associate Professor of Biological Sciences, College of Sciences, North Carolina State University
Dr. Scott Belcher is Associate Professor of Biological Sciences in the College of Sciences at North Carolina State University. His research efforts are highly collaborative and focused on understanding the role of endocrine disrupting chemicals on adverse disrupting chemicals of cellular signaling during development and disease progression.
One focus of the lab is to define the exposure and environmental health impacts of per- and polyfluorinated chemicals. Those studies use high resolution mass spectrometry approaches to characterize exposure of wildlife (American alligator and fish species) to define exposures, bioaccumulation, and potential adverse health effects resulting from exposures to these emerging contaminates concern.
Clinical Director, South African Prostate Cancer Study (SAPCS)
Riana Bornman completed a degree in medicine, trained as an andrologist in Male Reproductive Health, and later became head of Andrology dealing with male infertility and the aging male. She found her true passion with Community-based Research in the Vhembe District, Limpopo Province, focusing on human and environmental health concerns of insecticides used for malaria control. She is the South African Principal Investigator for USA based National Institutes of Health (NIH) and Canadian Institutes of Health Research (CIHR) funded studies performed in a field office at Tshilidzini Hospital, Thohoyandou.
Riana was a founding member of the South African Prostate Cancer Study (SAPCS) and is the Clinical Director. She leads participant engagement (South Africa) and is a clinical researcher in public health in South Africa.
Associate Professor/Graduate Program Director, Department of Environmental Health Sciences, University of Massachusetts Amherst, School of Public Health and Health Sciences
Dr. Laura Vandenberg is an Associate Professor and Graduate Program Director in the Department of Environmental Health Sciences in the University of Massachusetts Amherst, School of Public Health and Health Sciences. Trained as a developmental biologist and endocrinologist, Dr. Vandenberg’s laboratory research examines the effects of endocrine disrupting chemicals, and in particular, compounds that mimic estrogens. She is especially interested in the effects of these compounds on function and disease of the mammary gland, and on maternal behaviors.
Outside of the lab, her research critically evaluates issues that affect risk and hazard assessments for endocrine disrupting chemicals including low dose effects, non-monotonic dose responses, critical windows of susceptibility, routes of exposure, and methods used to evaluate hazard. Dr. Vandenberg is an author on more than 80 peer reviewed papers and ten book chapters. She has served on a number of US and international expert panels to assess endocrine disrupting chemicals, and is regularly asked to speak at conferences around the world.
Catherina Van Zijl
Senior Scientist, Environmental Chemical Pollution and Health (ECPH) Research Unit
Senior Scientist, Department of Urology, Steve Biko Academic Hospital
Extra-ordinary lecturer, School of Medicine, Department of Urology, University of Pretoria
Catherina Van Zijl is the Senior scientist in the Environmental Chemical Pollution and Health (ECPH) Research Unit. She is also the Senior Medical Natural Scientist in the Department of Urology at the Steve Academic Hospital, and holds an Extra-ordinary lecturer position the School of Medicine in the Department of Urology at the University of Pretoria. She completed her PhD in Environmental Health in the School of Health Systems and Public Health on “Estrogenic Activity, Target Endocrine Disrupting Chemical Levels and Potential Health Risks of Bottled Water and Water from Selected Distribution Points in Pretoria and Cape Town” in 2017.
She has worked in the field of endocrine disruption since 2003. As the EDC laboratory manager and an expert in cell culture techniques she has taught many Hons, MSc, and PhD students how to perform and interpret the complex bioassays (estrogenic, androgenic, and thyroid activity) to determine EDC endpoints in various matrices. She is involved in a number of Water Research Commission (WRC-SA), Global Water Research Coalition (GWRC), Medical Research Council (MRC-SA), CANSA, and NRF funded research projects, with a special interest in endocrine disrupting chemicals, bioassays, reproductive toxicology, and environmental health. She has authored and co-authored several technical reports and peer reviewed publications.
Dr Van Zijl’s research focus is on the effect of endocrine disrupting chemicals in the environment (focus on water), food packaging materials, and the effects of exposure on male reproductive health.
Tiaan de Jager
Dean of the Faculty of Health Sciences, University of Pretoria
Professor in Environmental Health, School of Health Systems & Public Health (SHSPH), University of Pretoria
Extraordinary Lecturer in Andrology, Department of Urology, School of Medicine, University of Pretoria
Director, UP Institute for Sustainable Malaria Control (UP ISMC)
Tiaan de Jager is currently the Dean of the Faculty of Health Sciences, University of Pretoria (UP), South Africa. He occupied the post of Deputy Dean Research for more than six years and Acting Dean from July 2016 to March 2017. Tiaan is a Professor in Environmental Health in the School of Health Systems & Public Health (SHSPH) and is an Extraordinary Lecturer in Andrology, Department of Urology, School of Medicine. He was Deputy Director: Medical Natural Sciences at Steve Biko Academic Hospital until 30 June 2003 and subsequently joined the SHSPH. He is also the Director of the UP Institute for Sustainable Malaria Control (UP ISMC).
Tiaan’s research career started in 1995 when he enrolled for his PhD (Reproductive Biology) in the Faculty of Health Sciences, UP. He graduated in 1996 and completed the UP Management Development Programme (MDP) in 1998. He conducted post-doctoral research at the Centre for Reproductive Biology Research, University Laval, Quebec City, Canada, from July 2000 - 2001. Tiaan managed an international epidemiological study in Mexico, creating long lasting international networks. He completed several international training courses, including the Reproductive Toxicology Programme at the University of Surrey, Guildford, (UK) and the Research Skills for Health Professionals Module at University of Oxford, Oxford, UK.
Tiaan is an internationally recognized researcher in his field. He has an extensive track record of knowledge dissemination, student supervision and project management. Currently, his various research projects focus on reproductive toxicology and environmental health; issues that are globally relevant in a climate of rapid population growth and increasing urbanisation. Tiaan coordinated research activities at the SHSPH before he took over the research portfolio in the Faculty of Health Sciences in 2012. He is the principal investigator on various projects of international standard and has established collaborations with leading scientists in Canada, Denmark, USA and Europe. Despite his numerous administrative responsibilities as part of the UP and Faculty executive, Tiaan maintains his research output, which is increasing in relevance and impact. Tiaan’s research has impacted on policy at national and international level, with the World Health Organization (WHO) and the United Nations re-evaluating methods for malaria control based on his findings. Nationally, Tiaan’s research has contributed to setting water quality guidelines.
In promoting UP’s vision to be a leading research‐intensive university in Africa, Tiaan, as Director of the UP ISMC, steered a bilateral discussion between the UP ISMC and the French Space Agency (CNES), through the French Embassy in South Africa, to explore the potential of a joint research collaboration using remote sensing in an effort to eliminate malaria. The Remote Sensing and Malaria Control in Africa (ReSMaCA) Programme was initiated following these discussions and has attracted international investors. Tiaan has also been leading a series of male reproductive health studies in the Limpopo Province, South Africa since 2003. He is the South African collaborator on an inter-sectorial and multidisciplinary team that aims to integrate skills, research designs and methods to investigate the effects of environmental toxicants on male reproductive health. This unique study compares the sperm epigenome of Greenland Inuit and South African indigenous men by combining expertise on spermatogenesis and sperm DNA epigenetics with cutting-edge genomics, computational biology, toxicology and epidemiology. He promotes multidisciplinary research by fostering mutually beneficial collaborations between regional, national and international experts and organisations, in line with UP’s vision of creating new knowledge and making a difference locally, but with global impact.